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Menstruation is a natural and beneficial monthly occurrence in healthy adolescent girls and pre-menopausal adult women. It concerns women and men alike as it is among the key determinants of human reproduction and parenthood. Differing approaches to menstrual hygiene management (MHM) have been associated with a wide range of health and psycho-social outcomes in lower income settings. This paper collates, summarizes and critically appraises the peer-reviewed and published evidence on the health and psycho-social outcomes of the methods of MHM used in low and middle income countries and to assess the evidence for existing interventions such as educational programs and absorbent distribution.